“Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications”

This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations.

With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.

Key Topics Covered:

Part One Concepts and Methods for Recombinant Drug Production

1 Pharmaceutical Biotechnology and Industrial Applications - Learning Lessons from Molecular Biology

2 Prokaryotic Cells in Biotech Production

3 Mammalian Cells in Biotech Production

4 Biopharmaceuticals from Plants

5 Production of Biopharmaceuticals in Transgenic Animals

6 Translation of New Technologies in Biomedicines: Shaping the Road from Basic Research to Drug Development and Clinical Application - and Back Again

Part Two Bringing the Drug into Action - From Downstreaming to Approval

7 Overview and Classification of Approved Recombinant Drugs

8 Downstream Processing

9 Characterization of Recombinant Proteins

10 Formulation Strategies for Recombinant Protein and Related Biotech Drugs

11 Drug Approval in the European Union and United States

12 Patents in the Pharmaceutical Biotechnology Industry: Legal and Ethical Issues

13 Biosimilar Drugs

14 Pharmacokinetics and Pharmacodynamics of Therapeutic Peptides and Proteins

Part Three Vaccines

15 Scientific, Technical, and Economic Aspects of Vaccine Research and Development

16 New Nanobiotechnological Strategies for the Development of Vectors for Cancer Vaccines

17 Recombinant Vaccines: Development, Production, and Application

Part Four Recent Applications in Pharmaceutical Biotechnology

18 In Silico and Ultrahigh-Throughput Screenings (uHTS) in Drug Discovery: an Overview

19 Metabolic Engineering of Medicinal Plants and Microorganisms for the Production of Natural Products

20 Metabolomics as a Bioanalytical Tool for Characterization of Medicinal Plants and Their Phytomedical Preparations

21 Integration of Biotechnologies for the Development of Personalized Medicine

22 Xenotransplantation in Pharmaceutical Biotechnology

23 Nutraceuticals-Functional Foods for Improving Health and Preventing Disease

Authors

Oliver Kayser.

Heribert Warzecha.

For more information visit http://www.researchandmarkets.com/research/h8nc6p/pharmaceutical_bio

Source: John Wiley and Sons Ltd