Evolution of Virulence in Eukaryotic Microbes offers a unique and up-to-date review of eukaryotic virulence in fungi, oomycetes, and protozoa parasites and how they affect both animals and plants. The only book to combine a discussion of human and plant pathogens, it takes a fresh look at the selective processes that have shaped the evolution of these organisms. Written by the world's top leaders in this area, the book explores advances in genetic tools, how pathogens exchange genetic material in nature, and the common themes of evolutionary adaptation that lead to disease in different hosts.

Key Topics Covered:

PART I GENERAL OVERVIEWS

- Population Genetics and Parasite Diversity

- Evolution of Meiosis, Recombination, and Sexual Reproduction in Eukaryotic Microbes

- Phylogenomic Analysis

- Phylogenetics and Evolution of Virulence in the Kingdom Fungi

PART II POPULATION GENETICS AND EVOLUTIONARY APPROACHES

- Malaria: Host Range, Diversity, and Speciation

- From Population Genomics to Elucidated Traits in Plasmodium Falciparum

- Selective Sweeps in Human Malaria Parasites

- Evolution of Drug Resistance in Fungi

- Discovery of Extant Sexual Cycles in Human Pathogenic Fungi and Their Roles in the Generation of Diversity and Virulence 1

- Worldwide Migrations, Host Shifts, and Reemergence of Phytophthora Infestans, the Plant Destroyer

- Experimental and Natural Evolution of the Cryptococcus Neoformans and Cryptococcus Gattii Species Complex

- Population Genetics, Diversity, and Spread of Virulence in Toxoplasma Gondii

PART III FORWARD AND REVERSE GENETIC SYSTEMS FOR DEFINING VIRULENCE

- Genetic Crosses in Plasmodium Falciparum: Analysis of Drug Resistance

- Genetic Mapping of Virulence in Rodent Malarias

- Genetic Mapping of Acute Virulence in Toxoplasma Gondii

- Virulence in African Trypanosomes: Genetic and Molecular Approaches

- The Evolution of Antigenic Variation in African Trypanosomes

- Antigenic Variation, Adherence, and Virulence in Malaria

- Invasion Ligand Diversity and Pathogenesis in Blood-Stage Malaria

PART IV COMPARATIVE "OMICS" APPROACHES TO DEFINING VIRULENCE

- Evolution of Virulence in Oomycete Plant Pathogens

- Evolution and Genomics of the Pathogenic Candida Species Complex

- Evolution of Entamoeba Histolytica Virulence

- Sex and Virulence in Basidiomycete Pathogens

- Emergence of the Chytrid Fungus Batrachochytrium Dendrobatidis and Global Amphibian Declines

- Impact of Horizontal Gene Transfer on Virulence of Fungal Pathogens of Plants

- Evolution of Plant Pathogenicity in Fusarium Species

- Genetic, Genomic, and Molecular Approaches to Define Virulence of Aspergillus Fumigatus

- Cryptosporidium: Comparative Genomics and Pathogenesis

Authors:

L. David Sibley.

Barbara J. Howlett.

Joseph Heitman.

For more information visit http://www.researchandmarkets.com/research/f33l8p/evolution_of_virul

Source: John Wiley and Sons Ltd